Ion channel cell lines

Ion Channel Cell Lines

SB's ion channel cell lines are available for commercial purchase under MTA. Flexible agreements are available based on proposed usage, such as academic research, in-house pharma / biotech usage or commercial CRO purposes. All cell lines have undergone rigorous functional validation and QC and are provided with validated culture SOPs.

Hear what our customers say:

As a startup, we initially relied on academic cell lines and transient transfections for obtaining IC50 values against a number of ion channels.  When the company grew, there was increasing pressure to produce more consistent results and to be able to share 
those results with investors and partners.  SB's ion channel cell lines were recommended to us by a number of pharmaceutical companies and CROs for being reliable, highly consistent, and well optimized. 

In our hands, cells from SB express good currents, are consistent from passage to passage and are easy to maintain and work with.  Their technical support is knowledgeable and helpful. We now use SB cell lines for both manual and automated whole-cell electrophysiology.

           - Senior Electrophysiologist, US Biotech

 

Sodium Ion Channel Assays

Voltage-gated sodium channel cell lines

Channel Species Host Cells Expression Price
Nav1.1 Human HEK Constitutive Inquire
Nav1.2 Human HEK Constitutive Inquire
Nav1.3 Human HEK Constitutive Inquire
Nav1.4 Human HEK Constitutive Inquire
Nav1.5 Human HEK Constitutive Inquire
Nav1.6 Human HEK Constitutive Inquire
Nav1.7 Human HEK Constitutive Inquire
Nav1.7 Monkey HEK Constitutive Inquire
Nav1.7 Dog HEK Constitutive Inquire
Nav1.8 Human HEK Constitutive Inquire
TRP Ion Channel Assays

TRP channel cell lines

Channel Species Host Cells Expression Price
TRPA1 Human HEK Constitutive Inquire
TRPA1 Rat HEK Constitutive Inquire
TRPA1 Monkey HEK Constitutive Inquire
TRPA1 Guinea Pig HEK Constitutive Inquire
TRPA1 Sheep HEK Constitutive Inquire
TRPC1 Human HEK Constitutive Inquire
TRPC3 Human HEK Inducible Inquire
TRPC4 Human HEK Inducible Inquire
TRPC5 Human HEK Constitutive Inquire
TRPC5 Mouse HEK Constitutive Inquire
TRPC5 Rat HEK Constitutive Inquire
TRPC6 Human HEK Constitutive Inquire
TRPC6 Mouse HEK Constitutive Inquire
TRPC6 Rat HEK Constitutive Inquire
TRPC7 Human HEK Inducible Inquire
TRPM2 Human HEK Constitutive Inquire
TRPM3 Human HEK Inducible Inquire
TRPM4 Human HEK Constitutive Inquire
TRPM4 Human CHO Constitutive Inquire
TRPM5 Human CHO Constitutive Inquire
TRPM5 Mouse CHO Constitutive Inquire
TRPM8 Human HEK Constitutive Inquire
TRPV1 Human HEK Constitutive Inquire
TRPV1 Rat HEK Constitutive Inquire
TRPV2 Human HEK Constitutive Inquire
TRPV3 Human HEK Constitutive Inquire
TRPV4 Human HEK Constitutive Inquire
TRPV5 Human HEK Constitutive Inquire
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Voltage-gated calcium channel cell lines

Channel Species Host Cells Expression Price
Cav1.2 Human HEK Constitutive Inquire
Cav3.1 Human HEK Constitutive Inquire
Cav3.2 Human HEK Constitutive Inquire
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Voltage-gated potassium channel cell lines

Channel Species Host Cells Expression Price
Kv2.1 Human HEK Constitutive Inquire
Kv2.1/9.3 Human HEK Constitutive Inquire
Kv2.2 Human HEK Constitutive Inquire
Kv3.1 Human HEK Constitutive Inquire
Kv3.2 Human HEK Constitutive Inquire
Kv3.4 Human HEK Constitutive Inquire
Kv4.3 Human HEK Constitutive Inquire
Kv4.3 KCHiP2 Human HEK Constitutive Inquire
Kv7.1 Human HEK Constitutive Inquire
Kv7.1/mink Human HEK Constitutive Inquire
Kv7.2 Human HEK Constitutive Inquire
Kv7.2/7.3 Human HEK Constitutive Inquire
Kv11.1-hERG Human HEK Constitutive Inquire
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Inwardly rectifying potassium channel cell lines

Channel Species Host Cells Expression Price
Kir2.1 Human HEK Constitutive Inquire
Kir2.2 Human HEK Constitutive Inquire
Kir2.4 Human HEK Constitutive Inquire
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Tandem pore domain potassium channel cell lines

Channel Species Host Cells Expression Price
K2P2.1 (TREK-1) Human HEK Constitutive Inquire
K2P3.1 (TASK-1) Human HEK Constitutive & Inducible Inquire
K2P4.1 (TRAAK) Human HEK Constitutive Inquire
K2P18.1 (TRESK) Human HEK Constitutive Inquire
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Calcium-activated potassium channel cell lines

Channel Species Host Cells Expression Price
KCa2.1 Human HEK Constitutive Inquire
KCa2.2 Human HEK Constitutive Inquire
KCa2.3 Human HEK Constitutive Inquire
KCa3.1 Human HEK Constitutive Inquire
KCa4.1 Human HEK Constitutive Inquire
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P2X channel cell lines

Channel Species Host Cells Expression Price
P2X1 Human 132N1 Astrocytoma Constitutive Inquire
P2X4 Human HEK Constitutive Inquire
P2X5 Human HEK Constitutive Inquire
P2X6 Human HEK Constitutive Inquire
P2X7 Human HEK Constitutive Inquire
P2X7 Mouse HEK Constitutive Inquire
Glutamate Receptors

Glutamate receptor cell lines

Channel Species Host Cells Expression Price
NMDA 1A/2B Human HEK Inducible Inquire
GluA2 Human HEK Inducible Inquire
Nicotinic Receptor Cell Lines

Nicotinic receptor cell lines

Channel Species Host Cells Expression Price
nAChR α7 Human HEK Inducible Inquire
Other Ion Channel Cell Lines

Other ion channel cell lines

Channel Species Host Cells Expression Price
TMEM16A (Ano1) Human HEK Constitutive Inquire
TMEM16B (Ano2) Human HEK Constitutive Inquire
HCN4 Human HEK Constitutive Inquire
ENaC Human HEK Constitutive Inquire