Ion Channel Drug Discovery

Driving Ion Channel Drug Discovery Research

At SB Drug Discovery, we recognize the diverse and complex ion channel research needs of our clients. To address this, we offer a flexible and innovative range of drug discovery solutions, utilizing the latest ion channel technologies and a comprehensive portfolio of electrophysiology assays , we are equipped to provide the necessary tools and expertise to support your ion channel drug discovery.

With our dedicated team and end-to-end ion channel screening capabilities, we deliver the results you need to advance your ion channel drug discovery research. Our services cover all aspects of ion channel screening, providing a convenient and consolidated solution to your research needs.

Access to the ion channel targets you need

SB Drug Discovery has successfully designed, generated, and validated over 150 recombinant ion channel cell lines. This extensive portfolio provides a wide range of options for your ion channel research, from HTS to off-target selectivity. Additionally, our optimized electrophysiology assays allow for efficient transition from ion channel screening to lead optimization. Throughout your research journey, you will have a single point of contact, ensuring a seamless and efficient service.

Discover tailored solutions with SB Drug Discovery, expertly adapted to your unique needs 

We recognize that our clients have varied and intricate ion channel research requirements. That is why we offer a flexible and innovative range of drug discovery solutions that include an extensive collection of ion channel screening and electrophysiology assays as well as customizable cell line generation capabilities, utilizing state-of-the-art technologies.

End-to-end ion channel screening services

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Target
Development

  • Expression validation
  • Cell line generation
  • Assay development
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High-Throughput
Screening

  • 96/384-well format
  • Fluorescence assays
  • Automated electrophysiology
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HIT Verification/
lead optimization

  • Dose-response studies
  • Routine screening
  • Selectivity profiling

Leading technologies for rapid, reliable results

Fluorescence-Based Screening

Fluorescence-Based Screening

We provide 96 and 384-well fluorescence-based screening solutions combined with state-of-the-art compound dispensing and analysis software to expedite ion channel screening campaigns.

Electrophysiology Studies

Electrophysiology Studies

Our 384-well automated patch clamp electrophysiology platforms are designed to respond to the numerous demands of your ion channel needs. With high-throughput screening capacity our automated platforms deliver the results you need to further the development of your next therapeutic discovery.

Manual Patch Clamp Electrophysiology

Manual Patch  Electrophysiology

To complement our high-throughput screening and automated electrophysiology services, we employ classical manual and two-electrode voltage clamp to enable detailed mechanistic studies.

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