Ion Channel Studies
Calcium Channels
Flexible assay formats
Our voltage-gated calcium channel capabilities extend from fluorescence-based screening assays to manual and automated electrophysiology. Benefit from our state-of-the-art automated patch clamp systems, optimized to deliver rapid insights into calcium channel function. Our flexible protocols can be customized to support high-throughput screening, selectivity profiling, and lead optimization studies.
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Voltage-Gated Calcium Channel Electrophysiology
Figure 1: Representative Cav3.2 current traces before (grey line) and during the presence of increasing concentrations of the blocker Verapamil (blue lines). Currents are obtained using a 200 ms step from -120 mV to -20 mV.
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