Ion Channel Studies

Nicotinic Receptors

Ion Channels

Available Nicotinic Receptor Targets

With robust cell lines and cutting-edge electrophysiology platforms, SB Drug Discovery supports your journey from hit identification through lead optimization. Our robust data and tailored approaches streamline and elevate your nicotinic receptor research.

Available Nicotinic Receptor Targets
nAChR α3β4
nAChR α4β2
nAChR α7

Flexible assay formats

SB Drug Discovery provides comprehensive nicotinic receptor assays via fluorescence-based assays and automated electrophysiology, ensuring that your assays are both reliable and effective.

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Nicotinic Receptor Electrophysiology

Figure 1: Representative NAchRα3β4 current traces before (grey line) and during the presence of increasing concentrations of the blocker Dihydro-beta-erythroidine (blue lines). Currents are obtained using a steady-state protocol at -80mV.<br />

Figure 1: Representative NAchRα3β4 current traces before (grey line) and during the presence of increasing concentrations of the blocker Dihydro-beta-erythroidine (blue lines). Currents are obtained using a steady-state protocol at -80mV.

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