Ion Channel Studies
Potassium Channels
Flexible assay formats
SB Drug Discovery offers an array of assay solutions for potassium channel research, employing fluorescence-based and electrophysiology assays. These versatile assays can be customized to meet specific requirements, facilitating the exploration of activators, inhibitors, and modulators essential for advancing innovative potassium channel therapeutics.
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Potassium Channel Electrophysiology
Figure 1: Representative Kv1.7 current traces before (grey line) and during the presence of increasing concentrations of the blocker Quinidine (blue lines). Currents are obtained using voltage protocol consisting of a pulse from -80 mV tp +40 mV over 200 ms.
Case Study
Electrophysiological characterization of functional and pharmacological effects of β subunit expression on BK channels
Discover how SB Drug Discovery’s comprehensive assays offer a pathway to novel insights, providing trustworthy data on calcium sensitivity, kinetics, activator and inhibitor profiling, reproducibility benchmarks, and I-V assays.