Transporter Drug Discovery
Custom cell-based tools and advanced technologies for transporter research
Advance your transporter drug discovery with SB Drug Discovery’s Transporter Discovery Platform, featuring custom cell-based tools and advanced technologies, to deliver robust data and accelerate your research.
Human Solute Carrier (SLC) transporters are essential proteins that regulate molecule and ion movement across cell membranes, supporting processes such as nutrient uptake, waste removal, and cell signalling. Their role in cellular balance makes them promising therapeutic targets, with dysfunction linked to cancers, CNS disorders, and metabolic diseases. SB Drug Discovery’s advanced assays, including binding, fluorescence-based screening, and solid-supported membrane electrophysiology (SSME), are designed to identify small molecule modulators and accelerate transporter-targeted drug discovery.
Custom assay development to accelerate your research
SB Drug Discovery’s target development group designs specialized assays precisely tailored to fit your unique discovery research needs. Our extensive assay capabilities enable fluorescence-based screening assays and state-of-the-art transporter electrophysiology to support identification of novel starting points for lead optimization. Working closely with your team, we customize assays to address project-specific challenges, delivering robust, reliable data that supports and enhances each stage of your drug discovery journey.
Leading technologies for rapid, reliable results
Fluorescence-Based Screening
Fluorescence-based screening assays offer fast, economical solutions to help identify novel modulators of SLC transporters. At SB Drug Discovery, our experienced team leverages high-throughput, 384-well fluorescence-based screening platforms, state-of-the-art compound dispensing technologies and advanced analysis software, setting the standard for excellence by delivering rapid and precise hit identification solutions for your SLC transport discovery needs.
Electrophysiology Studies
Our solid-supported membrane electrophysiology technology provides precise, reliable assessment of transporter activity. The SURFE2R 96SE enables real-time screening and characterization of compounds, delivering functional recordings of electrogenic transporters with high sensitivity and temporal resolution. This advanced system validates hits within native membrane environments, offering unparalleled versatility for your research.
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