Ion channels are among the most technically demanding targets in modern drug discovery. This free eBook outlines how Sygnature Discovery addressed these challenges through custom-built assays, specialist electrophysiology platforms and one of the largest ion channel portfolios available.
What This eBook Covers
- Custom Assay Development
From clonal cell line generation to validated pharmacology and tailored protocols
- Efficient, high-quality screening
Purpose-built platforms for hit-finding, SAR and selectivity profiling
- Mechanistic insights, not just readouts
Manual and automated electrophysiology to interrogate even the most complex or atypical targets
- Specialist support for rare and disease-relevant channels
Including lysosomal ion channels and clinically significant variants
- Integrated delivery from a single team
With access to DMPK, in vivo pharmacology, protein sciences and medicinal chemistry
Why Choose Sygnature Discovery for Ion Channel Discovery?
- 20+ years of ion channel leadership, with hundreds of programmes delivered across pharma and biotech
- One of the world’s largest ion channel panels, fully validated and ready for screening
- Scientific leadership in specialised areas, including lysosomal ion channels, clinically relevant variants and multi-species models
- More than data—real decision-making support, with expert interpretation embedded in every delivery
- One workflow from start to finish, with no hand-off gaps between disciplines
