With advanced expertise in transporter pharmacology, Sygnature Discovery leverages cutting-edge solid supported membrane electrophysiology (SSME) to deliver robust, validated insight into B0AT1 function. Our integrated cell-based platforms enable precise...
High-throughput, label-free functional profiling with SSME technology The human peptide transporter 1 (hPepT1 / SLC15A1) plays a critical role in intestinal absorption of di- and tri-peptides, peptide-based drugs and prodrugs such as cephalosporins, ACE inhibitors and...
Advance PAT-1 Drug Discovery with Custom Transporter Assays and High-Throughput Screening The proton-coupled amino acid transporter PAT-1 (SLC36A1) is a critical component of neurotransmitter precursor transport and nutrient absorption. Functioning via a 1:1...